I don't intend to disagree, merely to suggest that while doing the right thing one would be best off considering the potential aspects inflicted to themselves, in this case colonoscopy deaths are one in ten thousand from memory
To anyone wondering about this, I did it last year. You don't remember the procedure at all, you're just left with the blissful afterglow of the drugs they use to make you sleep. That stays with you for a couple of days. The uncomfortable part is the day before when you have to do a cleanse. Worth it.
> You don't remember the procedure at all, you're just left with the blissful afterglow of the drugs they use to make you sleep.
Technically this will vary depending on the protocol. I have friends in this field and in some countries they effectively knock you out with sedation. Others you might get some anxiety medication and only sedate elderly or uncollaborative patients.
Regardless of that everyone should absolutely get checked but just wanted to make sure we don't set unrealistic expectations.
Everyone who goes through the procedure says the same thing: it really is no big deal and the procedure itself is less of a problem than the laxatives you need to take the day before.
You are not going to catch the gay for having a colonoscopy, if that is your fear.
not sure if that makes it better for you, but usually you are knocked out and don't know what is happening during the procedure. Much worse is the preparation starting days before with disgustingly tasting things that intentionally give you diarrhea (and maybe make you puke) to clear the path, and no food at all
People get a safe but vile-tasting laxative by default. If you don't have any known problems with your colon then you could ask for a faster-acting laxative that is easier to get down.
I have a condition so I have a colonoscopy every year. Once I had found out about there being a fast-acting option, I've always chosen that.
I've never done it sedated. I prefer to watch the screen and and ask questions. I've found the view quite fascinating, actually.
The doctors and nurses have always been professional, focused on the colon: not the butt. There is absolutely nothing sexual about it. I've never felt pain: only some tension, and that's been because of gas (needed to get a clear view). It is perfectly safe unless your colon has some illness of some sort.
The worst part has always been the prep.
Yea I know, my life just isn't worth living and I'd prefer not to have something shoved up my ass to prevent something that could end it early cuz I am too foolish to do it myself.
I know it's difficult, but you should truly engage these thoughts now and then. You're pretty safe coming out in 2026, but it's understandable if you're worried about what your friends, family, and coworkers might think. Best thing you can do is just get real with yourself and admit to yourself that you are gay. The sooner you can end that internal struggle, the better.
The meme that homophobic people are in the closet is, in itself, not only factually wrong but also deeply homophobic.
It is factually wrong because, objectively, there are far more homophobes in conservative areas than there are gay people even in the most tolerant places.
And it is homophobic because it puts the blame of homophobia on the victims themselves. Yes, there are closeted gay and bisexual people who display performative homophobia to separate themselves from the LGBT community, but they are a tiny fraction of the homophobes.
I understand you mean well, but you are not helping the community.
Does this track differences between generations (i.e. environmental changes), or the age-related differences within a single cohort, or somehow both at once?
I wonder if the higher proportion of stromal cells in young tumors is a direct result of specific dietary components or gut microbiome variations rather than just inherent biology. The study mentions looking at how cell programs interact with diet and microbes, but it seems early onset cases often present with distinct inflammatory profiles in the colon itself before tumor formation.
It would be interesting to see if these long non-coding RNAs show up consistently in pre cancerous polyps in younger patients or only after malignant transformation. If they are elevated early on, that could actually help solve the diagnosis problem where many late stage cancers are found, assuming we can target them specifically.
Adenoma found and removed.
This is a type of cancer that is almost entirely preventable with screening. Get your tubes checked.
Had no symptoms, now I get one every 5 years.
Technically this will vary depending on the protocol. I have friends in this field and in some countries they effectively knock you out with sedation. Others you might get some anxiety medication and only sedate elderly or uncollaborative patients.
Regardless of that everyone should absolutely get checked but just wanted to make sure we don't set unrealistic expectations.
You are not going to catch the gay for having a colonoscopy, if that is your fear.
I have a condition so I have a colonoscopy every year. Once I had found out about there being a fast-acting option, I've always chosen that.
I've never done it sedated. I prefer to watch the screen and and ask questions. I've found the view quite fascinating, actually. The doctors and nurses have always been professional, focused on the colon: not the butt. There is absolutely nothing sexual about it. I've never felt pain: only some tension, and that's been because of gas (needed to get a clear view). It is perfectly safe unless your colon has some illness of some sort. The worst part has always been the prep.
It is factually wrong because, objectively, there are far more homophobes in conservative areas than there are gay people even in the most tolerant places.
And it is homophobic because it puts the blame of homophobia on the victims themselves. Yes, there are closeted gay and bisexual people who display performative homophobia to separate themselves from the LGBT community, but they are a tiny fraction of the homophobes.
I understand you mean well, but you are not helping the community.
It would be interesting to see if these long non-coding RNAs show up consistently in pre cancerous polyps in younger patients or only after malignant transformation. If they are elevated early on, that could actually help solve the diagnosis problem where many late stage cancers are found, assuming we can target them specifically.