30 comments

  • culi 3 hours ago
    > Now, three completely independent cultures have reported the same specific type of hallucination, and two cases are attributed to the same DNA-verified mushroom species. That indicates that these bizarre psychological effects aren't cultural manifestations or coincidences—they must have a shared underlying chemical and neurological basis.

    Rubroboletus sinicus is another species under investigation. Another bolete.

    The Chinese Daoist Ge Hong also wrote in Baopuzi around 300 CE about this effect from a mushroom and it seems to be common knowledge in pockets of China. Mushrooms that have this effect are collectively called xiǎo rén rén.

    I also found this bit funny from the Wikipedia:

    > In 2023, Lanmaoa asiatica received international media attention after U.S. Treasury Secretary Janet Yellen was reported to have eaten a dish that contained it during an official visit to China. Yellen stated that the dish had been thoroughly cooked, and she experienced no ill effects (hallucinations).

    • account42 3 hours ago
      > Mushrooms that have this effect are collectively called xiǎo rén rén.

      "Little people people" or does the second rén have a different meaning here?

      • eloisius 2 hours ago
        The effect of reduplicating is to make it diminutive. It like adding -ito to the end of a Spanish noun.
        • Eloissssss 24 minutes ago
          The usual Chinese expression to describe the mushroom hallucinations is 见小人 (jiàn xiǎo rén), literally “see tiny people.”

          Usually there isn't a second 人 (rén) being reduplicated here.

          人人 does mean “everyone,” but that's a different construction, and Chinese noun reduplication isn't generally equivalent to adding Spanish -ito. You may also see 小人儿 (xiǎo rénr), where 儿 is a colloquial/diminutive suffix.

        • plucas 1 hour ago
          Are you sure? I thought that's what "xiǎo" was doing here, with "rén" being repeated meaning "everyone".
          • eloisius 30 minutes ago
            I would defer to a native speaker, but Chinese is extremely contextual, and even native speakers often can’t tell you the formal rules of usage for something like this. There’s a lot more listening to register and intuiting intent required than with English. The same phrase used in different way can have a different function. In this usage it does not sound like plural “people” to my ears.

            You can say something like 「你看!可愛的狗狗」 and it’s “look! A cute doggy” (reduplicating 狗 gǒu). On the other hand you could say 「人人都知道她是小三!」 and it means “everybody knows that she’s (his) mistress!” (reduplicating 人 rén).

      • zarzavat 2 hours ago
    • bossyTeacher 2 hours ago
      It's funny how the Wikipedia article call hallucinations "ill effects". I am yet to hear people call caffeine effects "ill effects". People and their sociocultural biases, uh?
      • blks 0 minutes ago
        Unknowingly taking psychedelic substances is nothing positive, however positive outlook you may have on them.
      • embedding-shape 2 hours ago
        > I am yet to hear people call caffeine effects "ill effects". People and their sociocultural biases, uh?

        Coffee has well known ill-effects, I think every coffee drinker at one point have drank too much and felt them themselves. Apparently such a big topic that it isn't just a section of the Caffeine page, it has it's very own Wikipedia page! https://en.wikipedia.org/wiki/Caffeine_toxicity

      • dns_snek 2 hours ago
        > People and their sociocultural biases

        No, intent matters. If you drugged someone with caffeine (or someone drank it not knowing what it was) then their symptoms would also be called ill effects.

      • clarionbell 2 hours ago
        Seeing things that don't exist is generally detrimental to your short term survival.
        • gyomu 2 hours ago
          Arguably the long term survival and flourishing of the human species is due to humans being able to “see things that don’t exist”.
          • FeepingCreature 2 hours ago
            What a wild claim. You can't just say it's arguable, you have to actually argue it. Personally I think it's true but only in a metaphorical way that doesn't apply to hallucinogenic drugs; inasmuch as it applies to hallucinogenic drugs, it's false.
            • embedding-shape 1 hour ago
              I dunno if it's so wild, but maybe I'm zooming out way too much. The example that came to my mind was "mathematics", something that doesn't "exists" but we "see" it everywhere and humanity got massively improved thanks to it. Electricity would be another example :) I guess how wild the claim is depends on how charitable you read it.
              • FeepingCreature 1 hour ago
                Right, and I think any serious civilizational benefit of drugs in the sub-hallucinatory regime is at least unproven, and benefit in the hallucinatory regime doesn't exist. That's sorta what I mean: "where big, false; where true, not big."
                • gyomu 1 hour ago
                  > any serious civilizational benefit of drugs in the sub-hallucinatory regime is at least unproven

                  If you do want to get into the "where big":

                  Shamanic/ritual/religious/social practices that wholly involve hallucinatory experiences (both with and without the aid of hallucinogenic substances) are well attested and documented throughout human development.

                  So the existence is there; if you want to argue that actually it was a Bad Thing for human collectives, from Siberia to the Amazon, from 50k years ago to the present day, to engage in these practices and that they'd have been much better off Not Doing It, I guess the burden of that proof is on you?

                  • FeepingCreature 28 minutes ago
                    I don't think it was a Bad Thing; I'm not at all convinced it was a Good Thing. A Thing not being actively deleterious is enough to reach fixation.
                • embedding-shape 1 hour ago
                  > sub-hallucinatory regime is at least unproven, and benefit in the hallucinatory regime doesn't exist

                  It's a interesting train of thought if nothing else. How would we "prove" a thing like "humanity benefits from being able to create, share and read books?" for example? Or that we can organize in grassroot movements? It's also really hard to qualify directly, as the impact is so indirect.

                  Same with psychedelics, a lot of scientists, researchers, creatives or even business-people attribute psychedelic usage to some of their success in their fields, but how can we really know if it was because of that or not?

              • imtringued 1 hour ago
                People don't see math or electricity with their eyes and it is simultaneously hard to argue that their physical counterpart doesn't exist. Your examples are things you can't see but exist.

                Your analogy is exactly backwards.

                • embedding-shape 1 hour ago
                  > People don't see math or electricity with their eyes and it is simultaneously hard to argue that their physical counterpart doesn't exist. Your examples are things you can't see but exist.

                  How is that different from psychedelics? We can "see" their physical counterparts (and chemical reactions) in people's head and body as they trip too.

            • close04 1 hour ago
              I read it as “we can see with our imagination”. We build, we invent, we follow our “hallucinations” whether they come from drug use or just an active imagination giving revelations.
          • bossyTeacher 2 hours ago
            I couldn't have phrased it better.
      • awestroke 2 hours ago
        The large majority of people want absolutely nothing to do with hallucinations
        • cactusplant7374 1 hour ago
          The religious will love them if they arrive naturally. There are even a few studies that administered psilocybin to religious professionals. They described it as the most profound experience of their life.
      • LoganDark 2 hours ago
        Are you talking about caffeine dependence? For many people, caffeine itself feels beneficial.
        • bregma 1 hour ago
          So does social media. Keep scrolling man, just one more hit.
        • inigyou 2 hours ago
          So does meth.
  • yreg 5 hours ago
    The researchers seem pretty convinced that this mushroom causes the hallucinations yet they do not describe trying it out in an experiment.

    Surely the most straightforward way is to undercook the mushrooms and run a blind controlled experiment where participants eat the shrooms and report on hallucinations.

    What stopped them?

    • novia 4 hours ago
      > the trips it produces are unusually long, commonly lasting one to three days after an onset of 12 to 24 hours, and in some cases even causing hospital stays of up to a week. Because of the extraordinarily long duration of these trips and the chance for prolonged side effects such as delirium and dizziness, Domnauer has yet to try the raw mushrooms himself.

      > These mega-trips might help to explain why people in China, the Philippines and Papua New Guinea do not seem to have a tradition of purposefully seeking out L. asiatica for its psychoactive effects, according to Domnauer's findings. "It was always just eaten for food," Domnauer says, with hallucinations being an unexpected side-effect.

      From when this same story was covered in January

      https://www.bbc.com/future/article/20260121-the-mysterious-m...

      • rbanffy 3 hours ago
        > lasting one to three days after an onset of 12 to 24 hours

        I’ve been to parties longer than that.

        • ramon156 1 hour ago
          Well, sign yourself up!
          • rbanffy 35 minutes ago
            That time is long past, but I still embrace my inner dude.
      • culi 3 hours ago
        Sounds very similar to an anti-cholinergic/delirious effect rather than a psychedelic one. More similar to Datura than Psilocybe
        • carljungslabtek 2 hours ago
          It kind of does, just because people see spiders and all other kinds of “real” things on datura or benadryl, but I “tripped” on benadryl a few times in high school and it was very “non-euclidean” every time. The laws of physics were not obeyed, and the hallucinations are a lot scarier than goofy little people falling over themselves.

          So if the experiences really are real, it sounds to me like something wholly unique. Apparently there are no recorded deaths from the lilliputian mushrooms, and the long onset is weird too because anticholinergics come on very quickly.

          There are psychedelic phenethylamines that last 24 hours or more, so I don’t think the duration is a sign of anything really.

        • bossyTeacher 2 hours ago
          I don't think you can put Datura in this scale at all. Datura is borderline psychotic inducing. More damage you might not heal from than funny visuals.
          • embedding-shape 2 hours ago
            We're talking psychedelics, they're all borderline psychotic inducing, that's why we like and consume them :)

            Datura is definitively a different beast, and definitely something I'd recommend others to stay away from even if I and my friend was dumb enough to consume it when we were young. LSD, mushrooms and friends are 100x better and more fun.

    • lukan 3 hours ago
      Do you volunteer?

      3 day non stop trip sounds .. not great, if it ain't great.

      • bragr 2 hours ago
        I don't know. 3 days, even if it is great, doesn't sound great. Trip reports from long lasting research chemicals all seem pretty awful.
      • mettamage 2 hours ago
        Sure, I'd do it. One bad month tops. I can take that.
    • piker 4 hours ago
      Maybe the prospect of seeing tiny people? Stops me!
    • colordrops 4 hours ago
      They might be neurotoxic.
      • stuaxo 2 hours ago
        All the best stuff is.

        /s

        • inigyou 2 hours ago
          Ordinary psychedelics are thought to induce neuroplasticity.
    • wellthisisgreat 4 hours ago
      Tiny people
    • theelous3 1 hour ago
      > Domnauer has yet to try the raw mushrooms himself

      Coward, basically. I have no idea why on earth you'd travel the world looking for a specific hallucinogen and then just try to sequence it and toss it, and then waste everyone's time writing papers saying you essentially have a hunch about the mushroom's effects.

      Beyond terrible science.

    • s1artibartfast 4 hours ago
      I assume knowlege of the experiment could influence the outcome.

      I think you would have to dose people without knowledge of that phenomenon

      • QuantumNomad_ 4 hours ago
        Couldn’t you get consent from the participants to consume hallucinogenic substances but also getting them to agree that there will be a number of trials and they won’t know which one if any of them will actually contain it?

        So instead of a single experiment where half of the people get it and half don’t, the experiment will be repeated ten times with the same people over a few months, different meals each time and in total each person will get hallucinogens in their food either zero or one times.

        And then you see what effects people report and if that correlates well with who was actually given the hallucinogens, and if there is a lot of placebo among the rest of the people each time that they were not given hallucinogens.

        • freehorse 3 hours ago
          1. The main problem I imagine is not consent but ethics approval. You are probably gonna find some experienced psychonauts curious enough to want to try, but getting it approved by an ethics committee I imagine being tricky.

          2. Multiple times per person over months risks attrition which gonna mess it up, and the statistical power increase you get could be offset by that (eg if a person gets it they may not be motivated to come again for the placebo). On the other hand ppl may be more motivated if they know they are gonna get it at least once so dunno.

          3. Placebo with hallucinogens is always tricky. I would use psilocybin as (extra or only) control, esp if you test for little ppl. This way you can test if they report more tiny ppl in the new mushroom vs psilocybin.

        • leni536 4 hours ago
          What if the hallucinogen has long term health effects? What if tiny people show up for a participant years from the experiment, while driving?

          I guess you can be upfront about unknown unknowns, and most human experiments have some of those, but I assume there are standards to keep those to a minimum.

      • eru 2 hours ago
        > I assume knowlege of the experiment could influence the outcome.

        That's why you do randomisation and double-blinding.

    • forestrywat 5 hours ago
      Presumably the fact that experimenting on oneself is not considered particularly ethical or repeatable for science?
      • derektank 4 hours ago
        There’s nothing unethical about self experimentation. There are many notable examples of it in the history of science. Most notable is probably Barry Marshall’s decision to self-dose with helicobacter pylori, in an effort to prove that the bacteria caused ulcers. They did, he treated himself with antibiotics, and he was later awarded a Nobel for the research. Werner Forssman also won a Nobel for work partially derived from self-applying a cardiac catheter.
        • wraptile 4 hours ago
          Barry Marshall's story is so iconic that I read it every time despite knowing it very well.

          That being said one claim here would be that allowing self-experimentation would pressure people into self experimenting due to how our academia and labs are structured these days i.e. a junior scientists could be pressured into self experimentation by their superiors. So this is definitely not as clear-cut as one might think.

          • VBprogrammer 4 hours ago
            > Barry Marshall's story is so iconic that I read it every time despite

            As someone who suffered badly with ulcers in my teens I'm particularly grateful for his work. One course of antibiotics and I never had that problem again.

          • Zobat 2 hours ago
            > Barry Marshall's story is so iconic...

            More so for him and his collaborator having dinner each year when the Nobel prizes were announced in anticipation of the call from the Nobel Prize Committee. Legends.

        • kapep 2 hours ago
          > There’s nothing unethical about self experimentation.

          If people get rewarded for self experimentation, either directly with prices or indirectly with fame and success, more people will try do it. That certainly does raise ethical concerns. It worked out for people you mentioned but there will be many others who might harm themselves doing it.

      • dwattttt 4 hours ago
        I'm not sure what ethical considerations come up when testing a medical hypothesis by self-administration. Famously Barry Marshall overturned decades of medical doctrine when he ingested helicobacter pylori, and demonstrated its role in gastritis (and I think providing evidence for peptic ulcers).
      • yreg 4 hours ago
        That's the feeling I got, that they've tried it out on themselves, but (understandably) neglect to mention it. Which is a shame, because the self-censorship isn't helpful in regards of getting to the bottom of this.

        But maybe I'm reading too much into it.

      • _joel 2 hours ago
        You need to learn about this guy then https://en.wikipedia.org/wiki/Alexander_Shulgin
      • leni536 4 hours ago
        It's probably not ethical. How repeatable it is is for an experiment to decide, if it was possible to arrange ethically.
        • yreg 4 hours ago
          What's unethical about it? It sounds the locals consume it anyway. If the experiment is blind you can even tell the participants what is it about beforehand without losing too much validity.
          • leni536 4 hours ago
            I don't know much about standard ethical frameworks used in these kinds of experiments, but giving hallucinogens with unknown long term health effects to participants feels somewhat unethical to me.

            Also, to get stronger results you would probably want to conduct the experiment on participants who don't have an expectation of seeing little people, so that rules out locals or people who heard of or eaten the mushroom before.

          • bonoboTP 3 hours ago
            Everything's unethical that seems kinda weird or icky to middle aged HR schoolmarm Karens who like to sit on committees and wiggle their fingers and clutch their pearls, like the good church ladies they are, at the naughty boys.
            • UpsideDownRide 2 hours ago
              There were some very questionable experiments done in the name of science that lead to development of ethics guidelines. Being respectful of other people is hardly pearl clutching
        • anon48293 4 hours ago
          Ethics are just someone else’s opinion.

          Something isn’t ethical or unethical, somebody just doesn’t like it. They might have a reason for it at best.

          • reichstein 3 hours ago
            Ethics is what people agree on. Not doing unnecessary harm is usually easily agreed on. Don't exploit people who know less it's also on the list. Doesn't mean we didn't learn something valuable from KZ camp experiments, we just don't think it outweighed the costs. And we don't like, or want to encourage, people who think it did.

            There are very strict rules for scientific experiments _because_ we know that without them, just guided by "common sense" or "be reasonable", someone would get blinded by ambition or "the potential" and go further than the majority want to accept.

            Anyone can "experiment" without it being an accepted scientific experiment. But then they're personally responsible for any and all bad outcomes. If you follow the rules and get the experiment pre-approved, you'll likely be covered by your employer's insurance and free from criminal liability . That's a very good incentive.

            • anon48293 9 minutes ago
              But people don’t agree on ethics. That’s the whole reason you have ethics boards. Otherwise the scientists wouldn’t need one since they already thought the same.

              I agree there ought to be rules, but ethics is just a word to make things sound fair when it’s just an authoritative decision, often taking bad arguments (like religious ones or public misconceptions) unnecessarily into account.

    • comboy 2 hours ago
      • embedding-shape 2 hours ago
        Is the argument that even if you'd do such an experiment with consent of the participants, it'd be unethical? Or are we just assuming this will be done without the consent of the participants?
  • dluan 3 hours ago
    These are pretty famous mushrooms in China. Right now Yunnan mushroom hot pot is all the rage, basically in every city in the country. It's also led to lots of tourists in Yunnan wandering around foraging for wild mushrooms. The problem is that there's hundreds of different types of mushrooms with varying levels of toxicity, and unless you grew up in the area and know what you're doing it's easy to get mixed up. There's plenty of videos on chinese social media of people giggling in hospital beds geeked out their gourds pointing at little people.
    • farfatched 2 hours ago
      Link? (To any of the above.)
  • dash2 5 hours ago
    > One person told me that while they were eating soup, the little people were jumping off their spoon into the bowl and swimming around. As they scooped a bite, the little people remained in their mouth.

    There’s definitely scope for a horror story here…

    • cubefox 3 hours ago
      Or a Disney animation.
  • misja111 4 hours ago
    I bet there is some mushroom species in Europe as well that contains that substance. All those stories about dwarfs, trolls etc. and especially in woody area's, they must have come from somewhere.
    • trencedamp 4 hours ago
      There's some variety of little people myth in most cultures. There's also giant myths in most and there's no mushroom for that.

      I think those kinds of myths are just natural progressions of exaggerations and oral storytelling

    • aflinik 3 hours ago
      Not sure about the exact same active substance, but Amanita muscaria is the obvious candidate. It's also commonly shown as part of the imagery in stories involving tiny people: the Smurfs, Super Mario (it's the power-up that makes Mario bigger/smaller), Fantasia, Alice in Wonderland, and so on.
    • Jolter 4 hours ago
      Folklore’s roots go deeper than a single species.

      Swedish tradition has it that trolls would replace human babies with their own babies. It does not take a long leap of imagination to to see how this could be used as an excuse for the practice of putting unwanted/deformed babies out into the forest ”for the wolves”. (Disclaimer: I don’t know how common that practice might have been, since it would presumably stem from prehistoric times)

      • fragmede 3 hours ago
        The question is could that possibly relate to Neanderthals or Denisovans co-exisiting with homo sapiens.
        • Jolter 3 hours ago
          Not in Sweden, as far as science knows. It’s a more likely explanation than orangutans, but not by much.
          • tokai 42 minutes ago
            Nobody lived in Sweden at that time.
  • adzm 4 hours ago
    Those who have used DMT often talk about machine elves. I imagine there is a part of the brain that specifically recognizes humanoid figures even in the distance that is getting overstimulated.
    • birdsongs 3 hours ago
      This is obviously just anecdotal, but when I was 6 I got very ill with the flu and was in bed for days. Super high fever and was quite out of it.

      I had a, idk, spell one afternoon where I saw this quilt we had on the wall open up at all the squares, and thousands of tiny people/elves poured out. They marched around carrying little boxes and were all around me.

      I remember it so vividly more than 30 years later because it freaked me out so much. Tried telling my parents about it and they just dismissed it as a nightmare, but I swear I was awake, just out of it with fever.

      Anyways, it was early 90's, and I know I was close to the dangerous temperatures of high fever. Perhaps the brain does interesting hallucinations in these situations?

      Have never hallucinated or had anything like that happen since.

      • boorang 2 hours ago
        likewise, the opening to Comfortably Numb always resonates.
      • phist_mcgee 3 hours ago
        I've hallucinated with fevers before, and they do feel surprising that you swear you are awake, but perhaps you're really in a twilight between awake and asleep and the dreams break through.
        • birdsongs 2 hours ago
          Yeah. To be clear I don't think anything mystical happened, it was just my brain doing very odd thing outside of its default state.
    • OroPla 2 hours ago
      I've read about someone "exploring" the DMT realm with the machine elves by putting a hundred or so willing participants into that state and they found that multiple participants encountered the same machine elf, so there's more going on than just that.

      Also, machine elves are not all humanoid. Some of them are complex geometrical shapes that are too complicated to parse. It was very fascinating to read about this phenomenon. I remember that what people described felt like some kind of Internet that is accesses with your consciousness.

    • TonyStr 4 hours ago
      Remember when stable diffusion would create image soups full of horrifying humanoid faces and figures? I imagine something similar happens when you dull the brain in the right way.
    • wraptile 4 hours ago
      your eyes are usually closed during DMT trip so I don't think your hypothesis stands.
      • xboxnolifes 3 hours ago
        Thankfully your brain continues working even when your eyes are closed.
    • colordrops 3 hours ago
      Assuming your model of reality is materialist and all of reality is created by grey matter, then yes.
  • ulrikrasmussen 3 hours ago
    I think this is so fascinating because the hallucinations sound unlike anything else produced by psychedelics and other psychoactive substances, so I really look forward to learning what the mechanism is.

    From the stories I've read it also doesn't sound people are experiencing outright delirium although the experience can probably be pretty stressful if you don't know what is happening.

    • farfatched 2 hours ago
      Do we understand the mechanism behind any hallucinations?
      • ulrikrasmussen 1 hour ago
        Maybe not, I don't know. But at least we understand the pharmacology of many of them, which I guess is what I actually meant.
  • AnodicElegy 1 hour ago
    Domnauer is overstating the "little people" effect here. Seeing miniaturized people seems to be only one of several manifestations associated with these mushrooms. This Wikipedia article (https://en.wikipedia.org/wiki/Hallucinogenic_bolete_mushroom) is a lot more informative. To me, it sounds like it could actually be a serotonergic substance, but it's not clear. I hope they find the active constituent!
  • wglb 5 days ago
  • yanhangyhy 4 hours ago
    its a hot online topic when talking about YunNan province of china.its a land of all kinds of mushrooms/(and bugs). If you eat mushroom hotpot in there, the waiter will lock the pot and put a timer on the table, before the time limit hit, you cannot open and eat..cooks long time helps reduce the chance of position.

    this tv show ( meet youself, cast by Liu yifei, who also played Mulan(2020)) has a short part is about the 'tiny people': https://www.youtube.com/shorts/jVoza_qE3ww

    • dudefeliciano 2 hours ago
      > all kinds of mushrooms/(and bugs)

      And cannabis. It's hippy heaven.

  • vsviridov 5 hours ago
    Half of the plot of Common Side Effects :)
    • ColdStream 3 hours ago
      Absolutely brilliant show. Highly recommend it to anyone. Feels like a hyper condensed version of the X-files but with a decent sense of humour to it as well.

      Season two will be out next year and I am curious to see how it goes. Towards the end of season one, the side effects were starting to get interesting, possibilities of it turning dark abound.

      I'm just glad that after Joe Bennets previous show Scavengers Reign got axed after one season that we will finally get to see some of his stuff expanded.

  • undebuggable 5 hours ago
    Most of weird European and Middle Eastern legends and fairy tales originate from drugs or encountering real artifacts or phenomenons which they couldn't explain. Look up how cyclops appeared in mythology.
    • ghgr 5 hours ago
      In case you're wondering like me, I think parent is referring to elephant skulls being mistaken for one-eyed, giant creatures.
      • anentropic 59 minutes ago
        Wasn't that later debunked though?
      • undebuggable 3 hours ago
        Ancient Greeks were finding skulls of dwarf elephants during masonry works and quarrying in Sicily.
      • Schlagbohrer 5 hours ago
        I assume the global mythology around dragons comes from finding dinosaur bones
        • lesostep 3 hours ago
          Well, eastern dragons always reminded me more of a giant oarfish. And some central europe dragons weren't that far off, being described as flying snakes.

          I think "every culture has a dragon" is kinda misleading.

          "Every culture has a creature that got translated as a dragon" seems closer to the truth. The creatures themselves have a great variety between them.

        • s1artibartfast 4 hours ago
          Seems like many bones would do. Whales would be a lot more common i imagine.
  • agnosticmantis 3 hours ago
    Wondering if the hallucination also occurs to other animals?

    Would dogs taking the L. asiatica see little humans or little dogs? Probably neither, but then does that mean the fungus had targeted humans genetically?

    • fodkodrasz 3 hours ago
      > does that mean the fungus had targeted humans genetically?

      very utilitarian and anthropocentric world view.

      Why would a random thing in the world specifically targeting humans with some niche effect? Did cocoa plant target humans specifically with its pleasing flavor (after having been heavily processed), while being toxic for many other animals?

      • cachius 2 hours ago
        Why would a random thing in the world specifically target anything? Nature throws things against the wall and keeps what sticks.

        Look at https://en.wikipedia.org/wiki/Hedychrum_rutilans, a parasite on a parasite. Did it target beewolves specifically? And now its hosts are dying, was it his fault he chose the 'wrong' target?

        Not the anthropocentricity is to criticise, but the idea of nature targeting. OP asked a well meaning question where sth. can be be learned from. Thank you.

        • fodkodrasz 2 hours ago
          The whole targeting phrasing mixes cause and effect. Evolution, as we currently understand it, is working differently: it is random effects and seeing what sticks, as you phrased, not targeting anything specifically.

          The level of consciousness where the phrase targeting makes sense is way higher.

    • elliotec 1 hour ago
      We know with extremely high certainty that classical psychedelics effect other animals similarly given the neuroscience [1]. But this is not a classical psychedelic. We don't know how it works yet, what receptors it operates on, or what the pharmacology is doing.

      So would dogs see little humans or little dogs? We can't say for sure. But the best guess might actually be most likely little dogs, or maybe little smells of little dogs. Dogs show conspecific preference (species-focus) while we show facial preference [2] and they have a strong focus on olfactory sense while we're more visual. The vividness might show up in ways we can't really perceive through smell like they can.

      And the answer to "does that mean the fungus has targeted humans genetically" is almost definitely no. The study the article is based on [3] mentions that lilliputian hallucinations predate this mushroom, appear across cultures' folklore, and are reported in alcohol withdrawal, dementia, and macular degeneration. The effect seems fundamental to how the human mind and brain work. So it's more likely that the mushroom is disrupting something and the brain is resolving that disruption into little people, because that's what it does with pattern matching.

      This mushroom is an ectomycorrhizal symbiote of the Yunnan pine tree, is ancient with the genus being at least 5 million years old compared to modern humans 300k, and requires undercooking which isn't compatible with human targeting so it doesn't make sense to have any genetic human target.

      The fungus supplies a non-targeted disruption and the resulting little people content we describe is the human brain's response. A dog getting the same disruption would resolve it into whatever a dog's machinery produces, or maybe they metabolize it into nothing recognizable.

      Pretty damn cool.

      [1] https://consciousnesslibrary.org/research/29070-correlation-... [2] https://www.jneurosci.org/content/40/43/8396 [3] https://consciousnesslibrary.org/research/27751-phylogenomic...

  • user20180120 2 hours ago
    What about DMT and a laser experiment?

    The Unexplained Laser Experiment That Breaks Reality

    https://m.youtube.com/watch?v=W5YiFEghnrw

  • ipsum2 4 hours ago
  • jmkd 1 hour ago
    Somewhere there are tiny people going "Don't let the giants eat those mushrooms!"
  • recursivecaveat 4 hours ago
    I once spoke with a family member who was experiencing hallucinations of little people at the moment. So I guess if you want to experience this at home you can try giving yourself a head wound. Not as active or vivid as described I think though, they just said that the little people were hanging out up in curtains peering at us.
    • lesostep 3 hours ago
      That reminded me. Almost 20 years ago, there was a city folktale that some species of Convolvulus could get you high, and my friend tried it and then described seeing little knights playing|fighting on a wallpaper. I was a designated spotter, and didn't know what to do, so I just wrote down everything she said. Still should have a notebook somewhere.

      (It was 2 specific species out of 200, and I hope that not mentioning which part of the plant she ingested would deter people from trying. The plant is also slightly poisonous, could weaken your kidneys. Weak kidneys no fun)

      • culi 3 hours ago
        Probably meant Ipomoea (morning glory. It's actually a fungus on the seeds not the plant itself)
  • guerrilla 3 hours ago
    Nothing like that in Europe? Explain gnomes and ferries.
    • toilet 3 hours ago
      Ferries are a type of public transport people use to traverse bodies of water.
      • reverius42 2 hours ago
        And Gnomes are popular desktop environments.
  • ra 4 hours ago
    I've often wondered if the fairies and leprechauns of Ireland and the pixies of Cornwall were due to some psychoactive mushroom people used to eat.
  • qwertyboy 4 hours ago
    Annoyingly misleading title. From the article:

    Lilliputian hallucinations predate this mushroom. There are myths about tiny people in pretty much every culture's folklore. People have also reported these hallucinations from alcohol withdrawal, dementia, macular degeneration and other neurological conditions. So, it seems like this phenomenon is fundamental to how the human mind and brain work, but we don't know what causes it or how to treat it.

    That's what makes this mushroom different — it reliably produces this effect

    • j16sdiz 3 hours ago
      What make this research paper different -- this is the first genetic study of this mushroom.
  • noduerme 5 hours ago
    I'm surprised they sent it for analysis and no one just ate one to check for hobbits...
  • karim79 3 hours ago
    Goddamn ant men. Can't get rid of 'em.
  • andrewstuart 5 hours ago
    I can imagine the packaging of it being sold commercially
  • LoganDark 5 hours ago
    I can't wait until this compound is identified and available somewhere (incl. black markets). I would love to try it just out of curiosity.
    • waysa 2 hours ago
      Why wait? Book a flight to Yunnan, order a tasty mushroom soup or get a fresh batch from the markets.
    • Yuitea1 3 hours ago
      Realistically speaking, this substance causes irreversible damage to the kidneys and nervous system, so trying it is not recommended.
      • LoganDark 2 hours ago
        I would be inclined to agree in that case, but how do you know?
    • jamiek88 5 hours ago
      Fortunately, it’s inevitable. :D
  • roncesvalles 3 hours ago
    Babe wake up, a new psychedelic drug just dropped.
  • Yuitea1 3 hours ago
    I’m curious—do the people who have eaten these mushrooms see the same kind of "tiny people," or is "tiny people" just another name for the hallucination?
    • LoganDark 2 hours ago
      I don't think it's possible to exactly compare the experiences to see if one person's "tiny people" is the same as another person's "tiny people", but TFA does talk about literally seeing tiny people and not just calling something else "tiny people".
  • Schlagbohrer 5 hours ago
    Awesome
  • alpineman 2 hours ago
    "Using DNA sequencing"...sure bro
  • caniscrator 3 hours ago
    [flagged]