Reducing deaths is great, but shouldn’t they also mention the reduction in treatment (which is usually surgical or chemo, both of which are massively expensive, traumatic, and life altering in negative ways).
They could do that, but given how low the base rate is, the reduction in number of procedures (and the resulting negative impacts on the women) would be incredibly low. It seems the base rate for cervical cancer deaths under 30 was already near zero.
I don't know if there's young people here, but as someone that barely didn't make the cut to the new HPV-less generation. This is a gift that you need to take care of, don't take it for granted.
I fear that we have a risk budget, so when STD risk is reduced via a cure or prophylaxis, humans increase the amount of sex they have until the STD rate stabilizes again.
If this is the case, the benefit of a revolution in sexual health like this might be eroded in the long term by increased risky sexual activity until new STDs become prevalent enough to deter it.
So my recommendation to the younger generation, to whom this gift is bestowed by the previous generations, is to take care of it. It is evident that high partner counts, oral sex and anal sex are risky activities that can cause health problems, and also that it's very hard to attribute to the sexual event that caused it.
The previous generation lived through their own sexual health juncture, mostly marked by the aids epidemic and its aftermath, an ubiquity of condoms, a higher partner count, dating apps. I'm not being judgmental, just descriptive, it might have had some benefits and some consequences, even on the constrained topic of sexual health, but HPV along with cervical, throat and anal cancer lies squarely in the cons column of their lifestyle.
Now I was born in what I want to believe was a limbo between one generation and the other, I was born into a world where all of the things mentioned above were considered normal, and I might add where oral sex and anal sex were considered normal, were 90% of the population had HPV and the response from physicians was just "yeah, don't worry 90% of the population has that". I don't want to chastise the previous generation but you know, the goal of humanity is to progress, and while we definitely have to respect our elders and the traditions and values that we inherit, we can pick a select handful of behaviours to improve upon, and I think that valuing the temporal pleasures of oral sex with a temporary partner over our future health and that of our future spouses, would definitely make the cut into the top 5 mistakes to improve upon.
It's not anything revolutionary either, it's not so much progressism as much as it is a 180 degree return to traditions, a rejection of a specific form of progress: namely,
- Reduced partner count, ideally by marriage. Condoms are great, but nobody is going to wear a condom to go down, physicians that recommend that are just washing their hands. The next heterosexual epidemic will not be of the genital-genital route, it will be genital-oral, and in the world of concessions I'd bet my chips on marriage with oral sex, not on extremely prophylactic promiscuity or serial monogamy.
-Chill with the oral sex, weird to be explicit about this, but the degree matters too, it's a bit unnatural to avoid it completely, and any 'rule' or recommendation that bans it outright has the risk of being ignored, so let's just say that it's not the same to have some light contact to see how things are going, and to get ready for action, than to have it be the main course and do it to completion. Actually I'm not inventing anything here, this is 100% consistent with most religious views on oral sex, at least catholicism, where sex that is procreative, leads to or can lead to procreation is seen as healthy, and sex that derails from it is.. a derailment.
-Anal sex, just don't do it at all, I won't spend much time here, especially because it's an even more touchy subject due to how it relates to homosexuality, but let's just limit the scope to heterosexual sex . You know what each organ is for, previous generations might have called it design, we may call it evolution, but you know each part has its purpose, the anus is not for sex. Definitely 100% don't use any product that has anesthesics in it, I don't need to explain why that's horrible. Pain is your body telling you something is wrong, don't ignore it, don't get used to it, often getting used to some pain means that the signal is reduced or eliminated, not that the damage is.
- Hygiene: Again, sucks to be specific, but here it goes, clean stuff after using it. Don't go into scholar.google.com and look for the correlation between std rates and cleaning after sex or stuff like that, some stuff is simpler than that, just do it, the way you brush your teeth, nothing beats just dozing off after having sex, but even in the context of a long term couple with no huge STDs, it might cause candidasis, no need to apply fungal creams or take pills, just get up, even if you feel tired, turn on the sink, and take care of your beloved genitals.
- Avoid crossing routes: Viruses, and to some extent cell-based pathogens, usually spreads through specific routes. If you are going to break a rule, break one at a time, don't mix it all up. Won't go into details you know what I mean. Your partner might push back, and it's easy to be pressured whether man or woman, but it's healthy to have limits, and even in a couple context "no" is a sacred spell.
It felt weird to put this in writing, especially in the open and in a software forum, but I always engage in sexual health posts here, I think we have an interest in the subject because of its analogies with cybersecurity. Also as it often happens, I write for myself, and online forums are just a social medium that allows me to write what I otherwise would have never. These are things that I even wanted to communicate to my brothers or in the future my children, so maybe even in the future I will be able to go back to this post and share some knowledge, I'm no epidemiologist, or biologist or physician, I'm just a 30yo dude who has some tips that might save newcomers to the sexual world from irreversible damage.
My oldest daughter almost died from the first Gardasil, so you may not die from cervical cancer, but die from something else. I am not against vaccines; my kids are all fully vaccinated on a spaced-out schedule and not taking more than one shot in at least 2 months, and so am I, but the HPV vaccine was not mandatory, so, given the experience and the similar genetics, we didn't do it for the other two kids. Yeah, there's a risk of cancer, which might be curable 5-10-15 years from now, but the risk of side effects is here now... for some. So, it's not always a win-win, and we've got no interest from health authorities in assessing the risk for my other two kids, so they also seem very risk-averse and want us to assume all the negatives.
Just a note: the article focuses on the ladies, but men should absolutely get it as well because it cuts risk for other types of cancers. I was looking for a better link, however this is the only one I found (I had an older one saved, however I can't find it):
yes! Apparently the rate of penile and throat cancer occurs at only half the rate in men as it does as cervical cancer in women, but the harm caused by the male versions of the cancer are worse, so in actual fact it may overall cause more harm in the male population.
My bet is that it has to do with the mechanics of receptive vaginal and oral sex, the penis just reaches deeper and causes more lesions. Compared to insertive vaginal sex and oral vaginal performance, those lesions would be less frequent and on more distal parts of the body.
If the rate is 50%, I'd also expect MSM to be overrepresented there, which would make the difference of risk between heterosexual sex even more imbalanced.
For some reason not really talked about in mainstream medicine for straight men. It makes no sense. Very safe vaccine and you're eligible into your 40's to get it. Everyone sexually active probably has some strains but not all.
The vaccine presumably also protects those getting it when they are older, but the data doesn't show that yet. Still, if it does (as seems reasonable) then the benefit is even larger.
As mentioned already several times in the comments, there is also a long tail of people who survive but after a grueling and costly treatment that disrupt their lives.
Every time HPV comes up, someone says “guys should get the vaccine too” but I’ve never managed to succeed. Even after last time someone mentioned it I tried and I got the absolutely worst result where they recorded me as being given it but then said it wasn’t meant for men my age. Had to get it removed from the record by the One Medical people I saw next.
And when I saw them, they said it wouldn’t be covered under insurance and would be like $1.2k. I intended to just get it on my next visit to India but ended up not traveling.
I don’t get it. Is this like those Internet memes “don’t mess with the postal police” and stuff or is it a real thing? Any guy in their late 30s in the US who managed to get it?
American experience. It's free in Australia for people aged 12-25 and men who have sex with men (increased risks) and nothing like that price for private script.
I (male, 40s) paid Planned Parenthood in Florida for the three Gardasil doses out of pocket after the male age limit was raised to 45 circa October 2018 (as I wanted to ensure I was vaccinated before exiting the permitted age limit). Insurance covered it for my kids with no cost at their pediatrician.
In the UK it's commonly said, and the Guardian is a UK paper.
Though you've noticed a real thing: for some reason during and after the pandemic publications outside of the UK started saying it too and I don't know why.
In the UK, I believe jab has long been equivalent to shot in the US (complete with nonviolent connotation despite the word meaning something violent in other contexts).
> UK during the COVID-19 pandemic of 2021, when public health campaigns urged people to "get the jab."
Asked and answered, ty.
The term was popularized the US during the pandemic as well. It seemed like it was used by conservative media in the US to try to further politicize vaccination as something being inflicted on them.
The estimated number of deaths from cervical cancer in the US in 2026 is 4,200. The death rate is 2.2 per 100,000 people down from 3.1 per 100,000 in 1992.
If we multiply 3.1e-5 by 50 years that's about a 0.15% chance of dying of this cancer. The HPV shots cost $500-1000 for the three shots, so the cost per life saved is about $650K. With the statistical value of a human life being about $12M this is quite cost effective.
I'm assuming the reduction in death continues to later in life after 30, but that's a reasonable assumption, IMO.
Yep and significantly more than the death count would have needed expensive treatment and be out of the workforce for a time or permanently. Also the charged price isn't real cost to the economy. If they have a big margin on it after fixed research/approval expenses lots of it feeds back into the economy through taxes and dividends/reinvestment in other drug development.
Beyond death, it can also cause sterility and people may end up with extremely expensive IVF surrogacy pregnancies etc.
“Approximately 0.6 percent of women will be diagnosed with cervical cancer at some point during their lifetime, based on 2021–2023 data” [1].
Given “reports of serious health issues after HPV vaccination were consistently rare—around 1.8 per 100,000 HPV vaccine doses, or 0.0018%” [2], a woman suffers a 300x higher hazard (assuming we measure a serious vaccine reaction as being equivalent to cancer, which is silly) from going unvaccinated.
> How many people actually die of cervical cancer before age 30?
4,462 young women under the age of 30 died of cervical cancer in 2022 worldwide [3].
Your questions are sort-of answered in the article. 3300 die each year of cervical cancer in the uk. So at 0% it saves 3300 lives per year. However the vaccination is fairly new so they have to wait longer to see if it applies 20-years, 30-years, etc later. I assume it would though.
Out of curiosity, have there been any other advances in medicine that would make it less likely that women would die from cervical cancer before hitting 30? I don't keep up on oncology developments, but I assume that this particular shot is not the only thing that has reduced cervical cancer deaths in women under 30. If they were looking at rates of acquiring cancer, that would be more focused on this intervention.
So 5 deaths across 3 years? Doesn't seem worth a headline, especially since it could literally just be noise in the data.
Also, no need to post snarkily about LMGTFY. TFA should have included the base rate, and the fact that it didn't signals that it's not much of a reduction. It also signals that the journalist who wrote it is more in it for clicks than conveying accurate information.
Absolutely is - this is such a no-brainer of a public health intervention. We're not touching on the cost of treatment (including inability to have future children! very much something a State should be interested in avoiding).
Your answer reveals you are unable to analyse statistical data
There has always been deaths in the 20-24 y.o. slice since data collection started in 1970 and here we have 0 deaths between 2020 and 2024. If you can't work out that it is statistically significant, stop commenting about what is and isn't "noise" and learn statistics. And look at yourself in the mirror about giving lessons about "accurate information" and being "more in it for clicks".
The linked chart shows that there were none in the 20-24 age range during the during the recent few years. Is the entire population vaccinated? If not (the article doesn't claim this), then the fact that no one in that age range died (and only 5 in the entire under-30 cohort) tends to indicate that it was not a very high base rate.
Are there other sources that show data going back to the 1970s? Probably! I didn't go searching for them. I looked at what was linked above and saw there were very few. As I said, the Guardian journalist didn't include a base rate, which surely would have been included if it bolstered the argument.
EDIT: I just scrolled down further and saw that even the chart that shows trends over time (which I hadn't seen before, having stopped scrolling earlier) doesn't support your point. It shows there were roughly .2 deaths per year per 100k. Not having any deaths in 20-24 for 3 years is not a statistically significant difference, I would imagine, than the .2 figure. Also, there are undoubtedly other cancer-related advances that have made it less likely that a young woman would die of any kind of cancer.
And the data regarding under-30 deaths is muddled because the next bucket up is 25-34, and we don't know what it is up to 29.
Lastly, at the bottom there's this disclaimer, which makes it even harder to tell what's going on with small numbers:
> Note: Non-zero counts of 5 or less are suppressed and presented as 5.
If you have another source, please feel free to share. What we've seen so far (nothing in TFA, nothing of import in the commenter's linked data) isn't remotely compelling.
Your source doesn't say what you think it says, as evidenced by your other mistaken comments in this thread. I was referring to other sources (other than the one you posted, which doesn't say what you think it does) because I wanted to know if anything supported your claims.
Please stop with the ad hominem business, which is frowned upon by the HN guidelines (I see you're new here).
At one point, it was encouraged that 9-year-olds get the vaccine.
As a parent, I'd rather my child wait until their immune system is more developed, with the idea being that if they're getting STDs at age 9, then there's a bigger problem.
The only ones making the HPV vaccine "political" are the morons who think it shouldn't be administered because it increases promiscuity, or the ones who mistakenly think vaccines cause more harm than they help.
It has never been zero between 1970 and 2019. It has been completely 0 between 2020 and 2024.
Correct. These data are more a preview of what we can expect to see as the vaccinated cohort (in countries that aren’t pro-disease) advances in age.
https://www.health.gov.au/ministers/the-hon-rebecca-white-mp...
https://pmc.ncbi.nlm.nih.gov/articles/PMC13036706/
https://www.sciencedirect.com/science/article/pii/S009829972...
https://www.bbc.com/news/articles/cd6w15vgp7lo
I fear that we have a risk budget, so when STD risk is reduced via a cure or prophylaxis, humans increase the amount of sex they have until the STD rate stabilizes again.
If this is the case, the benefit of a revolution in sexual health like this might be eroded in the long term by increased risky sexual activity until new STDs become prevalent enough to deter it.
So my recommendation to the younger generation, to whom this gift is bestowed by the previous generations, is to take care of it. It is evident that high partner counts, oral sex and anal sex are risky activities that can cause health problems, and also that it's very hard to attribute to the sexual event that caused it.
The previous generation lived through their own sexual health juncture, mostly marked by the aids epidemic and its aftermath, an ubiquity of condoms, a higher partner count, dating apps. I'm not being judgmental, just descriptive, it might have had some benefits and some consequences, even on the constrained topic of sexual health, but HPV along with cervical, throat and anal cancer lies squarely in the cons column of their lifestyle.
Now I was born in what I want to believe was a limbo between one generation and the other, I was born into a world where all of the things mentioned above were considered normal, and I might add where oral sex and anal sex were considered normal, were 90% of the population had HPV and the response from physicians was just "yeah, don't worry 90% of the population has that". I don't want to chastise the previous generation but you know, the goal of humanity is to progress, and while we definitely have to respect our elders and the traditions and values that we inherit, we can pick a select handful of behaviours to improve upon, and I think that valuing the temporal pleasures of oral sex with a temporary partner over our future health and that of our future spouses, would definitely make the cut into the top 5 mistakes to improve upon.
It's not anything revolutionary either, it's not so much progressism as much as it is a 180 degree return to traditions, a rejection of a specific form of progress: namely,
- Reduced partner count, ideally by marriage. Condoms are great, but nobody is going to wear a condom to go down, physicians that recommend that are just washing their hands. The next heterosexual epidemic will not be of the genital-genital route, it will be genital-oral, and in the world of concessions I'd bet my chips on marriage with oral sex, not on extremely prophylactic promiscuity or serial monogamy.
-Chill with the oral sex, weird to be explicit about this, but the degree matters too, it's a bit unnatural to avoid it completely, and any 'rule' or recommendation that bans it outright has the risk of being ignored, so let's just say that it's not the same to have some light contact to see how things are going, and to get ready for action, than to have it be the main course and do it to completion. Actually I'm not inventing anything here, this is 100% consistent with most religious views on oral sex, at least catholicism, where sex that is procreative, leads to or can lead to procreation is seen as healthy, and sex that derails from it is.. a derailment.
-Anal sex, just don't do it at all, I won't spend much time here, especially because it's an even more touchy subject due to how it relates to homosexuality, but let's just limit the scope to heterosexual sex . You know what each organ is for, previous generations might have called it design, we may call it evolution, but you know each part has its purpose, the anus is not for sex. Definitely 100% don't use any product that has anesthesics in it, I don't need to explain why that's horrible. Pain is your body telling you something is wrong, don't ignore it, don't get used to it, often getting used to some pain means that the signal is reduced or eliminated, not that the damage is.
- Hygiene: Again, sucks to be specific, but here it goes, clean stuff after using it. Don't go into scholar.google.com and look for the correlation between std rates and cleaning after sex or stuff like that, some stuff is simpler than that, just do it, the way you brush your teeth, nothing beats just dozing off after having sex, but even in the context of a long term couple with no huge STDs, it might cause candidasis, no need to apply fungal creams or take pills, just get up, even if you feel tired, turn on the sink, and take care of your beloved genitals.
- Avoid crossing routes: Viruses, and to some extent cell-based pathogens, usually spreads through specific routes. If you are going to break a rule, break one at a time, don't mix it all up. Won't go into details you know what I mean. Your partner might push back, and it's easy to be pressured whether man or woman, but it's healthy to have limits, and even in a couple context "no" is a sacred spell.
It felt weird to put this in writing, especially in the open and in a software forum, but I always engage in sexual health posts here, I think we have an interest in the subject because of its analogies with cybersecurity. Also as it often happens, I write for myself, and online forums are just a social medium that allows me to write what I otherwise would have never. These are things that I even wanted to communicate to my brothers or in the future my children, so maybe even in the future I will be able to go back to this post and share some knowledge, I'm no epidemiologist, or biologist or physician, I'm just a 30yo dude who has some tips that might save newcomers to the sexual world from irreversible damage.
Stay healthy
Please forgive others in this insensible community who downvote you in spite of the terrible situation you had to deal with.
https://www.cnn.com/2026/04/24/health/hpv-men-vaccine-cancer...
If the rate is 50%, I'd also expect MSM to be overrepresented there, which would make the difference of risk between heterosexual sex even more imbalanced.
And when I saw them, they said it wouldn’t be covered under insurance and would be like $1.2k. I intended to just get it on my next visit to India but ended up not traveling.
I don’t get it. Is this like those Internet memes “don’t mess with the postal police” and stuff or is it a real thing? Any guy in their late 30s in the US who managed to get it?
https://sph.umich.edu/pursuit/2018posts/fda-approves-hpv-vac...
Though you've noticed a real thing: for some reason during and after the pandemic publications outside of the UK started saying it too and I don't know why.
Asked and answered, ty.
The term was popularized the US during the pandemic as well. It seemed like it was used by conservative media in the US to try to further politicize vaccination as something being inflicted on them.
The fact that they leave this out is a bit weird, sloppy journalism I guess.
I mean, vaccinations and cancer prevention are both great, but this headline is ridiculous.
If we multiply 3.1e-5 by 50 years that's about a 0.15% chance of dying of this cancer. The HPV shots cost $500-1000 for the three shots, so the cost per life saved is about $650K. With the statistical value of a human life being about $12M this is quite cost effective.
I'm assuming the reduction in death continues to later in life after 30, but that's a reasonable assumption, IMO.
Beyond death, it can also cause sterility and people may end up with extremely expensive IVF surrogacy pregnancies etc.
“Approximately 0.6 percent of women will be diagnosed with cervical cancer at some point during their lifetime, based on 2021–2023 data” [1].
Given “reports of serious health issues after HPV vaccination were consistently rare—around 1.8 per 100,000 HPV vaccine doses, or 0.0018%” [2], a woman suffers a 300x higher hazard (assuming we measure a serious vaccine reaction as being equivalent to cancer, which is silly) from going unvaccinated.
> How many people actually die of cervical cancer before age 30?
4,462 young women under the age of 30 died of cervical cancer in 2022 worldwide [3].
[1] https://seer.cancer.gov/statfacts/html/cervix.html
[2] https://www.cancer.gov/news-events/cancer-currents-blog/2021...
[3] https://gco.iarc.who.int/today/en/dataviz/pie?mode=populatio... Mortality, cervix uteri, females, 0 to 29
4,462 out of the whole population (of women etc.).
Would you subjectively describe that number as "almost zero"?
From the article:
“We estimate that since its introduction [in 2008], HPV vaccination has prevented nearly 200 young women from dying from cervical cancer in England.”
This is an estimate of 200 total of any age total across 18 years. The article doesn't say 3300 die each year, 3300 are diagnosed each year.
> Between 2020 and 2024, no cervical cancer deaths were recorded in women aged 20 to 24 - the first time that had happened over a five-year period.
> Without vaccination, around 23 deaths would have been expected.
Note the first chart in the link showing the historical trend for the 20-24 cohort since 2000 plumetting from 25 to 0.
The CDC mentions that not smoking and wearing condoms also lower the risk.
https://www.cdc.gov/cervical-cancer/prevention/index.html
Anecdotally people smoke less thant they uses to. Don't know what condom usage rates have done in the past quarter century.
> I assume that this particular shot is not the only thing that has reduced cervical cancer deaths in women under 30.
Why would you assume that when presented with a study that tracks with long standing belief in the medical community that the HPV vaccine works?
https://www.thelancet.com/journals/lancet/article/PIIS0140-6...
All the data is there:
https://crukcancerintelligence.shinyapps.io/CancerStatsDataH...
It was literally a google "death cervical cancer UK" away.
Also, no need to post snarkily about LMGTFY. TFA should have included the base rate, and the fact that it didn't signals that it's not much of a reduction. It also signals that the journalist who wrote it is more in it for clicks than conveying accurate information.
There has always been deaths in the 20-24 y.o. slice since data collection started in 1970 and here we have 0 deaths between 2020 and 2024. If you can't work out that it is statistically significant, stop commenting about what is and isn't "noise" and learn statistics. And look at yourself in the mirror about giving lessons about "accurate information" and being "more in it for clicks".
Are there other sources that show data going back to the 1970s? Probably! I didn't go searching for them. I looked at what was linked above and saw there were very few. As I said, the Guardian journalist didn't include a base rate, which surely would have been included if it bolstered the argument.
EDIT: I just scrolled down further and saw that even the chart that shows trends over time (which I hadn't seen before, having stopped scrolling earlier) doesn't support your point. It shows there were roughly .2 deaths per year per 100k. Not having any deaths in 20-24 for 3 years is not a statistically significant difference, I would imagine, than the .2 figure. Also, there are undoubtedly other cancer-related advances that have made it less likely that a young woman would die of any kind of cancer.
And the data regarding under-30 deaths is muddled because the next bucket up is 25-34, and we don't know what it is up to 29.
Lastly, at the bottom there's this disclaimer, which makes it even harder to tell what's going on with small numbers:
> Note: Non-zero counts of 5 or less are suppressed and presented as 5.
If you have another source, please feel free to share. What we've seen so far (nothing in TFA, nothing of import in the commenter's linked data) isn't remotely compelling.
I just gave the link with data going back to 1970...
You are not a serious person. Please stop being noise.
Please stop with the ad hominem business, which is frowned upon by the HN guidelines (I see you're new here).
It is not ad hominem to point out you don't search and you don't understand.
As a parent, I'd rather my child wait until their immune system is more developed, with the idea being that if they're getting STDs at age 9, then there's a bigger problem.
If kids are getting HPV before their teens, the solution is not vaccination ...